Using Menopur to Treat Infertility

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Menopur®
Menopur

Description:
This medication is known as a Gonadotropin. Menopur is an injectable, highly purified human menopausal gonadotropin (hMG). Each vial contains 75 IU (International Units) of powdered medication to be mixed with diluent.

How It Works:
Menopur is a gonadotropin that contains a combination of follicle stimulating hormone (FSH) and luteinizing hormone (LH) that stimulates the ovaries to produce eggs.

Potential Side Effects:
Side effects may include some local discomfort, bruising and soreness at the injection site. Changes in mood, headache, abdominal discomfort, nausea, bloating and cramping are other possible minor side effects. Multiple births occur in about 20-25% of pregnancies of which 70% are twins. Excessive enlargement of the ovaries, called ovarian hyperstimulation (OHSS) may occur. Symptoms of OHSS include excessive fluid retention and severe abdominal discomfort. If you experience an allergic reaction: difficulty breathing; closing of throat; swelling of lips, tongue or face; or hives; seek emergency attention immediately. And if at any time you experience pain, warmth, redness, numbness, or tingling in an arm or leg; confusion, severe dizziness or severe headache, seek medical attention immediately. PLEASE NOTE: If these or any other side effects occur, contact your physician.

If you experience an allergic reaction: difficulty breathing; closing of your throat; swelling of your lips, tongue or face; or hives; seek emergency medical attention immediately. And if at any time you experience bone pain, difficulty urinating, numbness, tingling or weakness in the arms or legs contact your physician immediately.

PLEASE NOTE: If these or any other side effects occur, contact your physician.

Storage:
Store Menopur at room temperature or refrigerate. Menopur cannot be mixed in advance. Once mixed, it must be used within 15 minutes.


Mixing

 

 

Pop off the plastic top of powdered medication and diluent (liquid).

Swab the top of each vial with an alcohol pad to prevent contamination.

Remove the 1 ½” needle from the 3cc syringe and attach the Q-Cap.

Holding the syringe, draw back 1cc of air into the syringe.

Place the spike end of the Q-Cap over the top of the sterile diluent vial, and firmly push down until the Q-Cap spike is through the rubber stopper. Press down on the plunger of the air filled syringe to transfer the air into the vial in order to equalize the pressure, which will make withdrawal of the diluent easier. Invert, or turn upside down, the syringe with Q-Cap and vial as one complete unit, and withdraw 1cc of the diluent. Remove the Q-Cap and syringe from the vial by pulling on the syringe barrel.

Hold the Menopur vial in one hand, grasp the sides of the syringe in the other hand and place the tip of the Q-Cap over the top of the vial and push the Q-Cap through the rubber stopper. Slowly and cautiously deposit the diluent into the vial of powdered medication. Rotate the vial between your thumb and index finger until the solution is clear. Invert, or turn upside down the syringe with Q-Cap and vial as one complete unit and withdraw the contents of the vial.

Holding the syringe pointing upwards, twist the syringe counterclockwise while holding the Q-Cap steady to remove the syringe from the Q-Cap. Twist on the ½” needle for subcutaneous injection or 1 ½” needle for intramuscular injection. Tap the syringe to force any bubbles to the top. Depress the plunger to expel the air.

If you are mixing a single vial, you are now ready for your injection.
PROCEED TO SUBCUTANEOUS INJECTION INSTRUCTIONS

Mixing Multiple Vials

With Q-Cap still attached to the syringe, inject the contents of the syringe (powdered medication mixed with the diluent) directly into the next vial of powdered medication, slowly and cautiously. This will increase the dosage without increasing the liquid volume. Do not use more diluent for additional vials of Menopur. Again, rotate the vial between your thumb and index finger until the solution is clear.

Withdraw the newly mixed Menopur from the second vial back into the syringe. Repeat until you have reached your prescribed dosage.

Holding the syringe pointing upwards, twist the syringe counterclockwise while holding the Q-Cap steady to remove the syringe from the Q-Cap. Twist on the ½” needle for subcutaneous injection or 1 ½” needle for intramuscular injection. Tap the syringe to force any bubbles to the top. Depress the plunger to expel the air.

Subcutaneous Injection Instructions

Instructions


Injection Diagram

Cleanse your selected SUBCUTANEOUS injection site with an alcohol wipe and allow to dry.

While holding the syringe with your dominant hand between your dominant hand between your thumb and finger (as you would a pencil), pinch the skin (with your other hand) at the site you have selected.

With a quick, dart-like motion, insert the entire needle (up to the hub of the syringe) at a 90 or a 45 degree angle and depress the plunger slowly and carefully.

After the injection is complete, quickly pull out the needle. If bleeding, apply pressure to the injection site with a sterile gauze pad. If discomfort occurs after your injection, you may gently massage the injection site to alleviate your discomfort.

After injecting the medication, dispose of the syringe into the Sharps waste container. It is unnecessary to recap the needle as this could cause injury.

 

Intamuscular Injection Instructions

Menopur


Cleanse your selected INTRAMUSCULAR injection site with an alcohol wipe and allow to dry.

Hold the syringe with your dominant hand between your thumb and index finger (as you would a pencil). With your other hand, firmly stretch your skin at the selected injection site. Make sure you are using the intramuscular needle (usaully 1 1/2").

NOTE: To minimize bruising, firmly stretch the skin.

With a quick, dart-like motion, insert the entire needle ( up to the hub of the syringe) at a 90 degree angle into the stretched skin area between your thumb and index finger of the opposite hand.

Using either hand to stablize the syringe, pull back slightly on thee plunger and watch for blood in the syringe. (This is rare). You may feel slight resistance or see a small bubble -this is normal. If blood is not seen in the syringe, the needle is inserted properly. If blood appears in the syringe, DO NOT INJECT YOUR MEDICATIONS. Withdraw the needle, cover the site with a gauze pad, and apply pressure. Discard the syringe into the Sharps container. Repeat mixing and injection instructions.

Depress the plunger slowly and steadily.

Pull the syringe out in one motion.

After injecting the medication, dispose of the syringe into the Sharps waste container. It is unnecessary to recap the needle as this could cause injury.

Apply pressure to the site with a gauze pad and gently massage the area to help disperse the medication and relieve discomfort. Apply a bandage if necessary.

 
 
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